Use of novel cell
death inhibitors developed at BCRI to target drug from France delivery
tumors and reduce toxicity to normal tissue.
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New approaches to
protect normal cells during chemotherapy to limit drug
toxicity and/or increase drug dosages to more effective levels.
A method to
accurately monitor the effectiveness of chemotherapy
(based on identification of dying cells) during the initial days
of treatment that should lead to fewer failed therapie
study of a new, non-toxic herbal treatment for hard-to-cure,
drug-resistant ovarian cancer
characterization of a modified drug for the treatment of
prostate and ovarian cancer
study of a new protocol for the treatment of patients with
new mechanisms involved in death of cancer cells in response
to treatment (activation of “serine-proteases”) that will lead
to design of completely new treatment strategies.
Development of a new in vitro assay
to study drug effects on wound healing that does not require use
Studies on the mechanism of action
of the normal tissue component hyaluronate that promotes wound
Studies of mechanism of action and
clinical applicability of the new class of anti-tumor and
anti-viral drugs, cytotoxic ribonucleases (Onconase).